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1973 Albert Lasker Award for Clinical Research

For his development of the life-saving closed chest defibrillator and the pacemaker.

Award Citation
There are two kinds of cardiac rhythm disturbances in patients who have cardiac arrest: the rhythm disturbance of a heart in standstill; and the rhythm disturbance of a "fibrillating" heart, which are the commonest causes of death in acute heart attacks. The effective electrical techniques that now help to control these disturbances are the pioneering contributions of Dr. Paul M. Zoll.

Paul M. Zoll, M.D.  


Dr. Zoll demonstrated for the first time in 1952, that when a human
heart stops, it can be induced, by externally applied electric stimulation,
to resume beating.

Dr. Zoll's later studies showed that externally applied, alternating current counter shocks are similarly effective in stopping ventricular fibrillation, and also in correcting a number of other serious, potentially lethal, abnormalities of rhythm.

In addition, Dr. Zoll developed the theory and technique of continuous cardiac monitoring of heart rhythm, and was the first to apply this
method clinically. The Coronary Care Unit now found in every well-equipped hospital is a further development of this life-saving concept.

Pacemakers, which have saved thousands of people from sudden and unpredictable death, are Dr. Zoll's invention. One measure of the good that pacemakers have done, and the need there is for them, is the fact that more than 60,000 Americans have received pacemakers, and an estimated 12,000 to 15,000 new pacemakers are implanted annually.

For Dr. Zoll's many and brilliant contributions in this vital area of cardiac care, this 1973 Albert Lasker Clinical Cardiovascular Research Award is given.

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